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Early Trials- vaccine working/ new drug from Chinese

 
Barry 2020-05-18 15:58:12 

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Barry 2020-05-18 16:01:13 

Moderna has vaccinated dozens of study participants and measured antibodies in eight of them. All eight developed neutralizing antibodies to the virus at levels reaching or exceeding the levels seen in people who've naturally recovered from Covid-19, according to the company.
Neutralizing antibodies bind to the virus, disabling it from attacking human cells
surprised

 
Trinity 2020-05-18 16:04:33 

The link isn't working for me but I am familiar with the news. Thanks for sharing positive news we need it.

 
Barry 2020-05-18 16:19:32 

In reply to Trinity

Sorry working now- great news though very early and no peer review

 
Barry 2020-05-18 16:22:42 

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Caution


The data released Monday by Moderna is encouraging, but represents only a first step in a long process to bring a vaccine to market. It comes from an interim report on dozens of patients followed over weeks, whereas vaccine studies require broad testing in thousands of patients followed over many months or years.
Paul Offit, a vaccine expert at the Children’s Hospital of Philadelphia, said the data looked promising and it made sense to proceed to a large trial this summer
big grin

 
Drapsey 2020-05-18 16:38:32 

In reply to Barry

Paul Offit, a vaccine expert at the Children’s Hospital of Philadelphia, said the data looked promising and it made sense to proceed to a large trial this summer

Are you a volunteer for the trial?

 
sudden 2020-05-18 16:41:16 

i wonder how that links to this

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Slaoui, a former pharmaceutical executive, was named “chief scientist” on Friday for President Donald Trump’s “Operation Warp Speed,” a COVID-19 vaccine development operation. In order to take the new role, he stepped down from his position on the board of directors of biotech company Moderna Inc., which is based in Cambridge, Massachusetts. But Slaoui still owns 155,000 Moderna stock options, totaling more than $10 million as of Friday, according to Business Insider.

 
Drapsey 2020-05-18 16:44:08 

In reply to sudden

And the beat goes on ...

 
StumpCam 2020-05-18 16:52:40 

In reply to sudden

American Greed! twisted

 
Barry 2020-05-18 20:46:57 

Greed or not, it working cool

 
Chrissy 2020-05-18 21:07:28 

In reply to StumpCam
Works as well as Barry's prayer clothes or Jim Baker's snake oil.lol lol

 
sgtdjones 2020-05-18 21:54:55 

In reply to Chrissy

razz razz razz

 
Barry 2020-05-19 07:31:51 

In reply to Chrissy

You have evidence that the vaccine is not successful in early trials? I hope you find sense....

 
Barry 2020-05-19 07:35:54 

More details- I may love God but I am more than retired or drive trucks...

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The data comes from eight people who took part in a 45-subject safety trial that kicked off in March. The Moderna vaccine is one of more than 100 under development intended to protect against the novel coronavirus that has infected more than 4.7 million people globally and killed over 317,000.

Overall, the study showed the vaccine was safe and all study participants produced antibodies against the virus

 
Barry 2020-05-19 07:38:31 

Why are wicked atheists and the fat arse denying clear evidence? They want people to die... evil

 
Barry 2020-05-19 07:41:23 

In reply to Chrissy

I don’t know Jim Baker. He is a nasty man and a practical atheist...why are you attacking me- my moral code prevents me from entering Jessica Hahn confused

 
Barry 2020-05-19 07:45:27 

Instead of attacking believers, learn some science....

I am just reporting on an early trial

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Barry 2020-05-19 12:09:02 

Irresponsible- the story is carried in every press- snake oil my ...,., cool

 
Barry 2020-05-19 14:24:17 

Chinese find new drug working
Link Text big grin

 
Barry 2020-05-19 14:31:30 

From peer review article in Cell



Surprisingly, we found that 7 out of the 12 mAbs exhibited a strong RBD-binding affinity and a potent neutralizing ability against pseudotyped SARS-CoV-2 (Figure 5B and 5C). The neutralization abilities of three representative mAbs, BD-503, BD-508, and BD-515, were also verified in the PRNT against authentic SARS-CoV-2 and showed high potencies (Figure 5E and 5F). Moreover, these mAbs were mostly encoded by VH3-66/JH6 or VH3-53/JH6 gene segments for the heavy chain, and VLK1-9 or VLK1D-33/39 for the light chain (Figure 5C)

 
Barry 2020-05-19 14:32:45 

Source article
Yunlong Cao et al. Potent neutralizing antibodies against SARS-CoV-2 identified by high-throughput single-cell sequencing of convalescent patients' B cells, Cell (2020). cool

 
Barry 2020-05-19 16:28:37 

Is this also Jim Baker’s snake oil? lol

 
deanjones 2020-05-19 16:42:53 

In reply to Chrissy

Why would you root for a vaccine not to work? I know you hate Trump and I do to, but saving lives trumps (no pun intended) my dislike for him.

 
Barry 2020-05-21 00:24:23 

Attacked by Chrissy and now the Canadian fat arse- none did science in college... the woman say snake oil and ah buss a peer reviewed article from Cell that she can’t understand- now the fat arse come razz

 
Barry 2020-05-21 00:27:38 


The National Institute for Allergy and Infectious Diseases has partnered with Moderna on this vaccine. Scientists at NIAID made the vaccine’s construct, or prototype, and the agency is running the Phase 1 trial.


Although the agency did not comment, the results remain- gives us hope

 
Barry 2020-05-21 00:31:31 


Of the 30 patients who received the two lowest doses, only one reported a side effect considered to be grade 3: redness around the injection site. Three people who got the highest dose, 250 mcg, developed grade 3 “systemic symptoms,” including fever, muscle pain and headache, Moderna Chief Medical Officer Tal Zaks, M.D., Ph.D., said on a call discussing the data. Although the side effects were temporary and went away on their own, Moderna won’t carry the highest dose into future trials.

Based on the data, the company will tweak its phase 2 study to test two dose levels, 50 mcg and 100 mcg, while the NIAID will test a 50-mcg dose in all three age groups. Moderna thinks the phase 3 dose will land somewhere between 25 mcg and 100 mcg.

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Barry 2020-05-21 00:35:37 

News report- be balanced
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Barry 2020-05-21 01:54:37 

Fantastic video on the shortcuts being used
Link Text cool

 
Barry 2020-05-22 00:18:46 

Fatarse can’t keep us down cool